Category Archives: Cleanrooms

Pharmaceutical Manufacturing, Revisiting the Unexpected with Growth


To ensure that the manufacturing of pharmaceuticals is free from contamination, implementing a comprehensive cleaning and disinfection program is essential. Any modifications to the manufacturing process, such as introducing new equipment or materials, should be evaluated to confirm that the cleaning program prevents contamination. Maintaining a standardized change control process to document these updates is [Read More…]

Cleanroom vs. Controlled Environment

Cleanroom vs. Controlled Environment

What is the difference between a cleanroom and a controlled environment? Do you know what a Cleanroom (clean room) is? A cleanroom is  a controlled environment that restricts the number of pollutants or contamination to a specific number of particles per cubic foot or cubic meter. Cleanrooms are regularly tested to ensure they meet the [Read More…]

What are Pyrogens and Endotoxins…and How Can They Be Controlled in a Cleanroom

What are Pyrogens and Endotoxins?

Often, we use the terms’ bacterial endotoxin’ and ‘pyrogen’ interchangeably. They refer to phospholipid-polysaccharides (also termed lipopolysaccharides, or LPS). And there’s a chance that these pyrogens may be released from decaying Gram-negative bacteria such as E. coli. Following cell death, these complex macromolecules emanate from compromised outer cell walls. If unchecked, it can induce and [Read More…]

Stay Up To Date: How Much Do You Know About Controlling Gram-Negative Bacteria in a Cleanroom?


From cocci which are round in shape, to bacilli which look like rods, to spirals which are sub-classed according to the number of their twists per cell, microorganisms are fascinating little creatures. At least to those who study them. In structure, the three types are not only differentiated by shape but also by arrangement such [Read More…]

What is a Level 4 Biosafety Laboratory?


A Global Response to Coronavirus. In a headline image a floodlit cruise ship sits somberly in dock. In the foreground, buses ferrying passengers across the tarmac vanish into the dark Yokohama night. Flashing lights cast a red glow onto the metal fences separating the liner from the port, illuminating the quiet drama playing out under [Read More…]

From Mason Jars to Satellite Imaging


There are few things more iconic than a Ball Mason Jar. Beloved of homesteaders, canning fans, and smoothie-swigging hipsters alike, the dumpy glass jars with their two-part metal lids are – dare we say it? – screwed firmly into place in our society. Since its invention in the mid-1900s by John Landis Mason, the eponymous [Read More…]

Top 5 Articles of 2019

Cleanroom News Top 5

Happy New Year and welcome to 2020! Following the celebrations of ‘The Most Wonderful Time of the Year,’ you’ll be forgiven for experiencing ‘The Most Hungover Time of the (New) Year.’ Let’s face it – who did not overindulge during the holidays? So if you need a few minutes of peace and quiet to nurse [Read More…]

Retrieving Clean Samples From Mars


Welcome to 2020! A new year and a new decade that’s ripe with possibility and opportunity. A time to take stock, change life up a little (or a lot), and refocus on priorities. Maybe for you it’s a renewed commitment to better health? More conscious curation of your social media stream? Or perhaps it’s that [Read More…]

Brain-machine Implants From a Cleanroom

brain machine implant

It is the stuff of science fiction and of conspiracy theory. Brain-implantable chips that monitor our health, overcome physical limitations, improve memory, or track us, control our thoughts and manipulate our actions. Or even change the way we perceive and interact with reality. A technology to improve the lives of those living with a disability [Read More…]

Nootropics and the Testing of Cognitive Biohackers

nootropic cognitive brain

Back in 2011, a ‘wild card’ movie based on The Dark Fields, a science fiction novel by Alan Glynn, hit the box office to unexpected success. Grossing more than $160 million on a slender $27 million budget and starring Hollywood icons Robert De Niro and Bradley Cooper, the narrative follows writer Eddie Morra as he [Read More…]