Tag Archives: Cleaning Efficacy

Has Berkshire or a 3rd Party Performed Any Microbial Efficacy/kill Studies on the Satpax® Line of Presaturated IPA Wipers?

Satpax Canister

Question: Has Berkshire or a 3rd party performed any microbial efficacy/kill studies on the SatPax® line of presaturated IPA wipers? Answer: An efficacy/kill study has not been performed by Berkshire or a 3rd party lab for SatPax®.  Because of the number of variables involved when using wipes, it would be very difficult to produce meaningful [Read More…]

USP <797> Best Practices: Suggested Cleaning Frequency for Compounding Pharmacies


ISO Class 5 – Primary Engineering Controls (PECs) LAFWs – BSCs – CAIs – CACIs At the beginning of the each shift Before each batch No longer that 30 minutes after previous disinfection (during ongoing compounding) After spills When a surface contaminate is known or suspected Clean area after surface sampling (i.e. Contact Rodac Agar [Read More…]

Do CapSure® Wipers Leave a Residue on Surfaces?

Capsure logo

Q: Do CapSure® wipers leave a residue on surfaces? A: CapSure® treated wipers are not tacky, sticky or stiff and will not leave a residue on surfaces being cleaned. The patented (#8,431,497) surface treatment enables the wiper to capture and retain more particulate contamination than untreated wipers. The color, surface texture and hand of the laundered knit [Read More…]

EasyClean®360 Isolator Cleaning Tool – Q & A

Q: I have an application that requires a longer handle than comes with the isolator cleaning tool. Do you have any other handles that are longer that will fit the mop head? A: Our flat mop telescoping handle (BCR.T2HANDLE.1) will fit the EasyClean®360. It is fully autoclavable with a comfortable polypropylene grip. Its lightweight is ideal when fully [Read More…]

Can I Relaunder Cleanroom Wipes, and Use Them Again?


Can I Relaunder Cleanroom Wipes, and Use Them Again? Virtually all cleanrooms use wipers once then discard them.  In an effort to save money, some cleanroom personnel have considered relaundering wipers.  It is instructive to learn why relaundering wipers may not be a viable approach. Three factors are paramount: Levels of contamination on the wipers [Read More…]

Gamma Irradiated vs. Validated Sterile

Gamma Irradiated refers to a product that has been irradiated at some predetermined dose which is felt to kill the bioburden. Sterility testing is usually not performed nor quarterly audits for continued validation. The Sterility Assurance Level (SAL) cannot be predicted. A higher dose of radiation may be delivered to the product than may not [Read More…]

Isopropyl Alcohol (IPA): Still the #1 Choice in Cleanrooms


The most common liquid used for cleaning surfaces in the cleanroom is IPA, primarily because of its purity and consistency. Cleanroom operators sometimes ask if denatured alcohol can replace IPA in the cleanroom.  The simple answer is No.  Here’s why. Denatured alcohol is used for non-critical applications such as fuel for stoves, shellac thinner, and [Read More…]

Why Is Isopropyl Alcohol the Choice for Cleanroom Cleaning?


ISOPROPYL ALCOHOL (IPA) is widely accepted as a good liquid for keeping cleanroom surfaces in pristine condition. But what about methyl, ethyl, or butyl alcohol? Why aren’t these types of alcohols considered for cleanroom cleaning, too? It all comes down to performance, safety, and price. Methyl Alcohol And Evaporation At room temperature, methyl alcohol has three [Read More…]

How and When to Use Bleach in Cleanroom Cleaning


HOUSEHOLD BLEACH is well known for its ability to remove stains and whiten clothes during laundering. Bleach also finds application in health care facilities with cleanrooms. Such applications include aseptic pharmaceutical suites, biomedical device manufacturing and compounding pharmaceutical facilities that require the biocidal and sterilant capabilities of bleach. Bleach solutions, which are active against bacteria, viruses, [Read More…]

Should Cleanroom Cleaning Supplies Come From a Hardware Store?


YOU CAN BUY SOLVENTS like acetone and turpentine from a hardware store, but you really shouldn’t. Solvents sold in the hardware store are not refined to the level required for cleanroom cleaning. When applied to surfaces, the hardware store variety of solvents will leave visible residues behind after they have evaporated. Cleaning With Acetone Or Turpentine [Read More…]