Category Archives: Cleaning & Disinfection

Aseptic Cleaning, Cleaning & Disinfection, Knowledge Base

Endotoxins: A Danger to Pharmaceutical & Medical Device Manufacturing Industries

Posted on by Berkshire Corporation
Bacteria low endo
25
Apr

Introduction Pharmaceutical and medical device manufacturing personnel must cope with endotoxins – a contamination source unique to their industries.  Endotoxins, also known as pyrogens, originate from dead (!) gram negative bacteria. When this strain of bacteria are killed by antibacterial reagents (say phenolic or quaternary ammonium compounds), radiation, steam sterilization, etc. the cell wall detritus [Read More…]

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Berkshire Products, Cleaning & Disinfection, Knowledge Base

Are the Wiper Clips on the Ergonomic Cleanroom Flat Mop System Autoclavable?

Posted on by Berkshire Corporation
mop-clips
03
Apr

The yellow wiper clips are not autoclavable, but since they are detachable, simply remove them before autoclaving. All other components of the Ergonomic “V Mop” system are autoclavable.  The V shape allows it to slip smoothly into the pouches of the mop covers reducing bending and decreasing injury.  

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Cleaning & Disinfection, Knowledge Base

Disinfection of Cleanroom Surfaces With Hydrogen Peroxide

Posted on by Berkshire Corporation
Disinfection of Surfaces with Hydrogen Peroxide
12
Mar

Disinfection of Surfaces with Hydrogen Peroxide Of all the contamination control activities in a cleanroom, perhaps the most critical are disinfection procedures. That’s because human health depends on the quality and thoroughness of a surface disinfection wipedown. Many solutions can be considered for surface disinfection, but hydrogen peroxide and sodium hypochlorite (bleach) rate special attention. [Read More…]

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Cleaning & Disinfection, Knowledge Base

Disinfection of Cleanroom Surfaces With Bleach

Posted on by Berkshire Corporation
Disinfection-Surfaces-With-Bleach-_1_
09
Mar

A previous article in this series discussed disinfection of surfaces with hydrogen peroxide.  We turn our attention now to bleach as another very effective treatment agent. Most people understand that ordinary household bleach – a 5.5% solution of sodium hypochlorite (NaOCl) in water – is a strong disinfecting agent.  In neutral or slightly acidic solutions the active [Read More…]

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Aseptic Cleaning, Cleaning & Disinfection, Knowledge Base

How Do You Clean A Laminar Flow Hood?

Posted on by Berkshire Corporation
laminar flow hood cleaning
02
Mar

The EasyClean® 360 is the most efficient way to clean a laminar flow hood. It’s unique triangular shaped head allows it to clean the difficult tight corners in the hood.  The tool is delivered with two handles, a 14” (35cm) and 24” (61cm).  There is also another ordering option for a telescoping handle that will extend from 35 [Read More…]

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Berkshire Products, Cleaning & Disinfection, Knowledge Base

Can I Use a Cotton Swab in a Cleanroom?

Posted on by Berkshire Corporation
no cotton swabs
30
Oct

Faced with the problem of removing small bits of contamination in the cleanroom, you would probably have to invent the swab if it didn’t already exist.  You would soon find that this little “wiper on a stick” would also prove invaluable in cleaning delicate mechanisms, in precision surface cleaning and in removing residues in hard-to-reach [Read More…]

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Aseptic Cleaning, Cleaning & Disinfection, Knowledge Base

USP <797> Best Practices: Suggested Cleaning Frequency for Compounding Pharmacies

Posted on by Berkshire Corporation
isolator_cleaning
11
Oct

ISO Class 5 – Primary Engineering Controls (PECs) LAFWs – BSCs – CAIs – CACIs At the beginning of the each shift Before each batch No longer that 30 minutes after previous disinfection (during ongoing compounding) After spills When a surface contaminate is known or suspected Clean area after surface sampling (i.e. Contact Rodac Agar [Read More…]

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Cleaning & Disinfection, Knowledge Base

Sources of Cleanroom Contamination

Posted on by Berkshire Corporation
sources-of-contamination
27
Sep

SOURCES OF CLEANROOM CONTAMINATION What Are The Most Common Sources Of Contamination In A Cleanroom? People & Personnel Objects Fluids Tools Equipment Processes What Are The Most Common Types Of Cleanroom Contamination? Skin Particles Fibers Dust Grease Bacteria Viruses Metals Fungi NVRS (Non-volatile Residues) Ions Films DID YOU KNOW? Using Cheap Or Substandard Cleanroom Wipes [Read More…]

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Aseptic Cleaning, Cleaning & Disinfection, Knowledge Base

What is the Best Food Contact Surface Wipe?

Posted on by Berkshire Corporation
food contact
20
Jul

  Q: What is the Best Food Contact Surface Wipe? A: The best food contact compliant surface wipe must be tested by a third party lab for compliance with FDA 21 CFR regulations. The following Berkshire wipes have been tested and are compliant, written test results can be provided upon request.      

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Berkshire Products, Cleaning & Disinfection, Knowledge Base

What is the Best Cleanroom Wipe for Absorbing Oil?

Posted on by Berkshire Corporation
10
Apr

Pro-Wipe® OS This industrial wipe from Berkshire is engineered specifically to absorb and retain oil. The wipe complies with FDA CRF 177.1520 for food contact surface applications. It is an excellent choice in gel cap manufacturing for drying and polishing or any other application where oil needs to be removed.

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