What are the ideal cleaners and solvents for a cleanroom mop system?


Several common cleaners and solvents are available on the market for use with a cleanroom mop system. Knowing the most effective solutions can help you navigate your search with confidence. Note that the solutions mentioned below refer to the cleanroom-grade versions. If sterility is needed, they should have sterility certificates and be packaged in sterile bags, ready for cleanroom use.
Here are the eight most common cleanroom cleaning solutions to get your search started

1. Cleanroom-Grade Sporicide: This is a disinfecting chemical that specifically kills spores. It is an important part of a microbial contamination control strategy. Be sure to know if you need a sterile or non-sterile solution.

2. Cleanroom-Grade Quaternary Ammonium: These disinfectant cleaners are generally for non-food-contact surfaces and function as very good cleaning agents due to the high level of surfactants in the chemistry.  Residues are a concern and should be removed.

3. Cleanroom-Grade Phenolics: These compounds are generally used in hard surface disinfection and have excellent performance against bacteria, fungi, and viruses. However, they have come under regulatory scrutiny and can pose a hazard to human health.  They are known to have disposal restrictions in some areas.

4. Cleanroom-Grade Sodium Hypochlorite: This powerful disinfectant, commonly known as bleach, is widely available and comes in sterile and non-sterile versions. PPE will likely be required since it can be toxic and cause skin and eye irritation.

5. Cleanroom-Grade Hypochlorous Acid: This oxidizing agent is a much safer alternative to bleach. It is just as effective and poses little risk to human health since it degrades to salt and water.  Market formulations are typically low odor, low residue, and non-corrosive.

6. Cleanroom-Grade Hydrogen Peroxide: This oxidizing agent evaporates into water and oxygen, leaving very little residue on the surface. It’s usually non-toxic and non-flammable, making it a safer option for disinfecting.

7. Cleanroom-Grade Isopropyl Alcohol: This common sanitizer solution comes in bottles, sprays, wipes, and an aerosol mist. It effectively disinfects hard-to-mop surfaces like cleanroom grates.  It is useful for cleaning any disinfectant residues left on surfaces.

8. Cleanroom-Grade Water: Deionized or WFI water is perfect for general wipe-downs and rinses and can be mixed with other solutions. As deionized water has no minerals, it doesn’t leave any residue, spots, or stains on surfaces. Even if deionized water isn’t used as the primary cleanser, it’s an excellent rinsing agent that effectively removes all trace amounts of cleaning solution left behind.

Numerous cleanroom cleaning solutions are available; the eight solutions provided are just a starting point. After understanding your specific requirements, you will still need to make several decisions, such as whether you need spray bottles or gallons, a concentrated or diluted version, a sterile or non-sterile variant, and so on. The list of decisions should fit your operation’s specific needs and requirements.

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